BTRG

Biomaterials and Technology Research Group (BTRG)

Faculty of Dentistry, Universiti Malaya

About Us

The Biomaterials and Technology Research Group (BTRG) is a vibrant, multidisciplinary research team based at the Faculty of Dentistry, Universiti Malaya. As one of the faculty’s leading research groups, BTRG is dedicated to pushing the boundaries of innovation in dental and craniofacial biomaterials—from fundamental science to clinical application.

Our core mission is to develop, enhance, and evaluate dental materials and biomaterials that not only restore function but also ensure long-term biocompatibility, durability, and improved quality of life for patients. Through collaboration across disciplines—including dentistry, engineering, materials science, and biotechnology—we aim to turn cutting-edge ideas into tangible clinical solutions.

What We Do

Our research spans a wide spectrum of dental specialties and materials, reflecting the diverse and evolving needs of modern dental practice. We focus on materials used in:

• Cariology
• Endodontics
• Operative Dentistry
• Fixed and Removable Prosthodontics
• Maxillofacial Prosthodontics
• Denture Hygiene Products
• Orthodontics
• Paediatric Dentistry
• Oral Implantology
• Digital Dentistry
• Dental Traumatology

From conventional dental materials to advanced biomaterials and emerging technologies, our work combines laboratory testing, simulation of clinical conditions, and translational research to better understand material performance in real-world settings.

Our Key Research Areas

• Material Development & Enhancement

Improving the mechanical, physical, chemical, and biological properties of dental biomaterials.

• Environmental Testing & Simulation

Evaluating how materials perform under varying pH, temperature, humidity, and mechanical stresses—conditions that mimic the oral environment.

• Biomimetic Materials

Designing materials that replicate natural tissue structure and function for improved integration and healing.

• Translational & Preclinical Research

Bridging the gap between lab innovation and clinical practice, including collaboration with industry and pre-clinical trials.

• Smart & Advanced Technologies

Exploring novel materials such as bioactive surfaces, nanomaterials, and responsive hydrogels for regenerative applications.

Examples of Our Research:

• Functionally Graded Hydroxyapatite–Titanium Dental Posts – Engineered to optimise stress distribution and extend the life of endodontically treated teeth.
• Anisotropic Hydrogel Tissue Expanders – Designed for cleft lip and palate treatment, allowing precise and controlled soft tissue expansion.
• Eugenol Effervescent Tablets – An innovative, effective, and easy-to-use denture cleansing solution.
• Two-Colour Chewing Gum with Mastimeter Software – A novel method for accurately and quantitatively evaluating masticatory performance.
• Non-Setting Mineral Trioxide Aggregate (MTA) – Adapted as an intracanal medicament for improved root canal therapy outcomes.
• Magnesium–Bioactive Glass Nanoparticle-Enhanced PVA–Chitosan Hydrogel – Investigated for its potential to promote tooth remineralisation.
• Proteomics Analysis of α-Mangostin – Uncovering the antimicrobial mechanism of this natural compound for disinfecting dental impressions.
• Optical Evaluation of Aesthetic Restorative Materials and Enamel – Studying surface changes after exposure to energy drinks.
• Impact of Food-Simulating Liquids on Restorative Materials – Analysing performance through both dynamic and static testing.
• Staining Agents and Colour Stability in Digital Restorations – Examining how diet and environment influence long-term aesthetics.
• Hydroxyapatite-Coated Gutta-Percha – Enhancing adhesion between gutta-percha, sealers, and dentine for better root canal sealing.
• Chameleon Effect and Colour Stability of Nano-Filled Composites – Comparing blending ability and stain resistance from common dietary sources.
• Mechanical Properties of Lithium Disilicate CAD/CAM Blocks – Assessing strength, hardness, and microstructure to improve durability and aesthetics.
• Novel Glass-Infiltrated Zeolite Ceramic Cores – Exploring sodalite zeolite infiltration as a potential material for high-strength dental restorations.
• Silver Diamine Fluoride and Tooth Staining – Investigating the role of green capping agents in reducing staining while maintaining antibacterial and remineralisation effects.

These are just some of the ways we translate research into real-world impact, driven by our commitment to improve patient care through better materials.

Looking Ahead

At BTRG, we believe the future of dentistry lies in smarter, safer, and more clinically responsive biomaterials. We are committed to advancing research that supports evidence-based practice, shapes new treatment possibilities, and contributes to the global conversation on dental materials innovation.

We aim to be a leading regional hub for dental biomaterials research by strengthening academic, industrial, and clinical collaborations—locally and internationally.

Get Involved

We welcome students, researchers, and industry partners who share our passion for innovation in dental materials. Whether you’re interested in collaboration, research training, or exploring new technologies, we invite you to connect with us. 

Contact:

Prof. Dr. Noor Azlin Yahya

Head

Biomaterials & Technology Research Group

Email: nazlin@um.edu.my